Rapid development of API nanoformulations from ... ScienceDirect
Wet ball milling in a dual centrifuge (DC) (10100 mg API, 40 samples in parallel) was used to identify stable nanoformulations. In addition different sized agitator bead mills were used for scaleup to industrial scales. DCand smallscale agitator milling (AM) resulted in small and virtually identical APIparticles.